Dr. Kelley Yan has been awarded an NIH Director's New Innovator Award for “Directing Cell Fate Along the Intestinal Enteroendocrine Lineage.”

She is one of five Columbia scientists to receive NIH High-Risk, High-Reward Grants

October 7, 2020

Kelley Yan, MD, PhD, the Dorothy L. & Daniel H. Silberberg Assistant Professor of Medicine and Genetics & Development, has been awarded an NIH Director's New Innovator Award for “Directing Cell Fate Along the Intestinal Enteroendocrine Lineage.”

Yan’s lab uses multidisciplinary approaches to study the behavior of intestinal stem cells with the ultimate goal of manipulating them for therapeutic benefit.

In this study, Yan will focus on intestinal enteroendocrine cells that produce and secrete hormones involved in regulating body weight and energy expenditure. She will study how these cells develop and their involvement in human metabolic diseases. Through understanding these cells, she aims to harness their potential to treat human diseases such as obesity and diabetes.