Congratulations to Corey!
May 18, 2023
Congratulations, Corey!
Corey Garyn successfully defended his PhD thesis, "Mechanisms involved in the renewal and expansion of hematopoietic stem cells" on May 3rd, 2023. In Hans-Willem Snoeck's lab, Corey identified DNA damage and replication stress as a driver of direct megakaryopoiesis from hematopoietic stem cells (HSCs) both in vivo and in vitro. He also identified this mechanism as a major barrier to HSC culturing, and employed thymidine supplementation to avoid this pathway in culture.